Project data

Funding Entity: European Commission

Call: HORIZON-JU-IHI-2024-07-single-stage

Coordinator: EuResist Network GEIE (Italy)

UNISI Principal Investigator: Prof. Maurizio Zazzi

Department: Department of Medical Biotechnology (DBM)

Start date: 1 February 2025

End date: 31 January 2028

 

Description

Bioinformatics method to improve chronic disease management

Identifying virus-related biomarkers is crucial for managing chronic diseases, including those that indicate responses to antiviral treatments and virome characteristics that signal disease progression in immunosuppressed individuals. In this context, the EU-funded VIROMARKERS project aims to develop a bioinformatics method to predict HIV-1 susceptibility to monoclonal antibodies and assess treatment responses to bulevirtide using HDV RNA quantification and other biomarkers. It will validate serum CMV-RNA for infection monitoring in stem cell transplant patients and use biomarkers to guide antiviral strategies. The project will create diagnostic tools for HDV quantification, CMV-RNA detection, and TTV-DNA quantification, while outlining regulatory pathways for approval. Ultimately, VIROMARKERS seeks to provide effective biomarkers and technologies to address critical clinical needs and improve patient outcomes.

 

Source: CORDIS

 

Project website: http://www.viromarkers.eu

 

 

This project has received funding from the European Union’s Horizon Europe programme under GA No: 101194735