ComeInCell – Condensates at Membrane Scaffolds – Integrated Systems as Synthetic Cell Compartments

Project data

Funding Entity: European Commission

Call: Marie Skłodowska-Curie Actions (MSCA)

Coordinator: MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV  – Germany

UNISI Principal Investigator: Federico Rossi

Department: Dipartimento di Scienze fisiche, della Terra e dell’ambiente

Start date: 1 November 2024
End date: 31 October 2028

 

Description

Synthetic cells are artificially designed and constructed to mimic and understand the structure and function of biological cells. Multiple approaches are used to recreate cellular characteristics including compartmentalisation, metabolism, and responsiveness to stimuli. Synthetic cells hold great promise as tools for further insight in fundamental biological processes. With the support of the Marie Sktodowska-Curie Actions programme, the ComelnCell project will employ synthetic vesicles to study how membranes interact with biomolecular condensates: membrane-less organelles formed through liquid-liquid phase separation. Researchers will explore the role of these interactions in key cellular processes such as transport, metabolic networks, and repair.

Source: Cordis

Project website

 

This project has received funding from the European Union’s Horizon 2020 programme under GA No 101168939