Life Sciences (LS) | ONGOING PROJECT

PNRR – Tuscany Health Ecosystem (THE) – Chronic faecal microbial transplant to prevent aging-related pathologies and cognitive decline

27 January 2026 by

Project data

Funding Entity: Italian Ministry of University and Research (MUR)

Call:Tuscany Health Ecosystem (THE)

Coordinator: Università di Siena (Italy)

UNISI Principal Investigator: Prof. Eugenio Bertelli

Department: Department of Molecular and Developmental Medicine (DMMS)

Start date: 1 August 2023

End date: 31 July 2026

 

Description

This research aims to investigate the ability of the intestinal microbiota to mediate aging-related functional decline in many organs by performing fecal microbiota transplants from young donor mice to recipient animals throughout their entire lifespan. Behavioral, biochemical, functional, and immunohistochemical analyses will be conducted to evaluate whether the young microbiota has beneficial effects on normal aging.

 

Disclaimer: This project has been funded under the National Recovery and Resilience Plan (PNRR), Mission 4 Component 2 Investment 1.5 – NEXTGENERATIONEU, Project “Tuscany Health Ecosystem” (THE) – Spoke 2.